Inhibitory Activity and Docking Analysis of Antimalarial Agents from Stemona sp. toward Ferredoxin-NADP+ Reductase from Malaria Parasites

Ferredoxin-NADP+ reductases (FNRs, EC 1.18.1.2) were found in the plastids of Plasmodium and have been considered as a target for the development of new antimalarial agents. Croomine, epi-croomine, tuberostemonine, javastemonine A, and isoprotostemonine are isolated alkaloids from the roots of Stemo...

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Bibliographic Details
Main Authors: Pratiwi Pudjiastuti, Ni Nyoman T. Puspaningsih, Imam Siswanto, Much. Z. Fanani, Yoko K. Ariga, Toshiharu Hase, Satyajit D. Sarker, Lutfun Nahar
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Journal of Parasitology Research
Online Access:http://dx.doi.org/10.1155/2018/3469132