Entropic stabilization of proteins and its proteomic consequences.
Evolutionary traces of thermophilic adaptation are manifest, on the whole-genome level, in compositional biases toward certain types of amino acids. However, it is sometimes difficult to discern their causes without a clear understanding of underlying physical mechanisms of thermal stabilization of...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2005-09-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC1239905?pdf=render |