The TGFβ-signaling pathway and colorectal cancer: associations between dysregulated genes and miRNAs

The TGFβ-signaling pathway and colorectal cancer: associations between dysregulated genes and miRNAs

Abstract Background The TGFβ-signaling pathway plays an important role in the pathogenesis of colorectal cancer (CRC). Loss of function of several genes within this pathway, such as bone morphogenetic proteins (BMPs) have been seen as key events in CRC progression. Methods In this study we comprehen...

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Bibliographic Details
Main Authors: Andrew J. Pellatt, Lila E. Mullany, Jennifer S. Herrick, Lori C. Sakoda, Roger K. Wolff, Wade S. Samowitz, Martha L. Slattery
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Journal of Translational Medicine
Subjects:
TGFβ
Colorectal cancer
miRNA
mRNA
Online Access:http://link.springer.com/article/10.1186/s12967-018-1566-8

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http://link.springer.com/article/10.1186/s12967-018-1566-8

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