Master and servant: LINC00152 – a STAT3-induced long noncoding RNA regulates STAT3 in a positive feedback in human multiple myeloma

Master and servant: LINC00152 – a STAT3-induced long noncoding RNA regulates STAT3 in a positive feedback in human multiple myeloma

Abstract Background The survival of INA-6 human multiple myeloma cells is strictly dependent upon the Interleukin-6-activated transcription factor STAT3. Although transcriptional analyses have revealed many genes regulated by STAT3, to date no protein-coding STAT3 target gene is known to mediate sur...

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Bibliographic Details
Main Authors: Stefanie Binder, Ivonne Zipfel, Maik Friedrich, Diana Riedel, Stefanie Ende, Christoph Kämpf, Karolin Wiedemann, Tilo Buschmann, Sven-Holger Puppel, Kristin Reiche, Peter F. Stadler, Friedemann Horn
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Medical Genomics
Subjects:
STAT3
LINC00152
CYTOR
ncRNAs
IL-6 signaling
Epigenetics
Online Access:https://doi.org/10.1186/s12920-020-0692-3

Internet

https://doi.org/10.1186/s12920-020-0692-3

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