Inhibition of the TRAIL death receptor by CMV reveals its importance in NK cell-mediated antiviral defense.

Inhibition of the TRAIL death receptor by CMV reveals its importance in NK cell-mediated antiviral defense.

TNF-related apoptosis inducing ligand (TRAIL) death receptors (DR) regulate apoptosis and inflammation, but their role in antiviral defense is poorly understood. Cytomegaloviruses (CMV) encode many immune-modulatory genes that shape host immunity, and they utilize multiple strategies to target the T...

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Bibliographic Details
Main Authors: Shilpi Verma, Andrea Loewendorf, Qiao Wang, Bryan McDonald, Alec Redwood, Chris A Benedict
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4133390?pdf=render

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http://europepmc.org/articles/PMC4133390?pdf=render

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