Improved adherence adjustment in the Coronary Drug Project

Abstract Background The survival difference between adherers and non-adherers to placebo in the Coronary Drug Project has been used to support the thesis that adherence adjustment in randomized trials is not generally possible and, therefore, that only intention-to-treat analyses should be trusted....

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Bibliographic Details
Main Authors: Eleanor J. Murray, Miguel A. Hernán
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Trials
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13063-018-2519-5