Adjuvant Activity of Synthetic Lipid A of <i>Alcaligenes</i>, a Gut-Associated Lymphoid Tissue-Resident Commensal Bacterium, to Augment Antigen-Specific IgG and Th17 Responses in Systemic Vaccine

<i>Alcaligenes</i> spp. are identified as commensal bacteria and have been found to inhabit Peyer’s patches in the gut. We previously reported that <i>Alcaligenes</i>-derived lipopolysaccharides (LPS) exerted adjuvant activity in systemic vaccination, without excessive inflam...

Full description

Bibliographic Details
Main Authors: Yunru Wang, Koji Hosomi, Atsushi Shimoyama, Ken Yoshii, Haruki Yamaura, Takahiro Nagatake, Tomomi Nishino, Hiroshi Kiyono, Koichi Fukase, Jun Kunisawa
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/8/3/395