Platelet releasates promote the proliferation of hepatocellular carcinoma cells by suppressing the expression of KLF6

Abstract Platelets in the primary tumor microenvironment play crucial roles in the regulation of tumor progression, but the mechanisms underlying are poorly understood. Here, we report that platelet releasates exerted a proliferative effect on hepatocellular carcinoma (HCC) cells both in vitro and i...

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Bibliographic Details
Main Authors: Ao-Di He, Wen Xie, Wei Song, Yuan-Yuan Ma, Gang Liu, Ming-Lu Liang, Xing-Wen Da, Guang-Qiang Yao, Bi-xiang Zhang, Cun-Ji Gao, Ji-zhou Xiang, Zhang-Yin Ming
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02801-1