Potential role of senescent macrophages in radiation-induced pulmonary fibrosis

Abstract Radiation-induced pulmonary fibrosis (RIPF) is a late toxicity of therapeutic radiation in clinic with poor prognosis and limited therapeutic options. Previous results have shown that senescent cells, such as fibroblast and type II airway epithelial cell, are strongly implicated in patholog...

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Bibliographic Details
Main Authors: Lulu Su, Yinping Dong, Yueying Wang, Yuquan Wang, Bowen Guan, Yanhua Lu, Jing Wu, Xiaochun Wang, Deguan Li, Aimin Meng, Feiyue Fan
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03811-8