Analysis of the Epigenome in Multiplex Pre-eclampsia Families Identifies SORD, DGKI, and ICA1 as Novel Candidate Risk Genes

Pre-eclampsia is a serious heritable disorder that affects 5–8% of pregnancies worldwide. While classical genetic studies have identified several susceptibility genes they do not fully explain the heritability of pre-eclampsia. An additional contribution to risk can be quantified by examining the ep...

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Bibliographic Details
Main Authors: Amir Ariff, Phillip E. Melton, Shaun P. Brennecke, Eric K. Moses
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Genetics
Subjects:
DGK
ICA
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00227/full