Long, Noncoding RNA SRA Induces Apoptosis of β-Cells by Promoting the IRAK1/LDHA/Lactate Pathway

Long, Noncoding RNA SRA Induces Apoptosis of β-Cells by Promoting the IRAK1/LDHA/Lactate Pathway

Long non-coding RNA steroid receptor RNA activators (LncRNA SRAs) are implicated in the β-cell destruction of Type 1 diabetes mellitus (T1D), but functional association remains poorly understood. Here, we aimed to verify the role of LncRNA SRA regulation in β-cells. LncRNA SRAs were highly expressed...

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Bibliographic Details
Main Authors: Yu-Nan Huang, Shang-Lun Chiang, Yu-Jung Lin, Su-Ching Liu, Yen-Hsien Li, Yu-Chen Liao, Maw-Rong Lee, Pen-Hua Su, Fuu-Jen Tsai, Hui-Chih Hung, Chung-Hsing Wang
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
LncRNA SRA
LDHA
lactate
β-cell
type 1 diabetes mellitus
Online Access:https://www.mdpi.com/1422-0067/22/4/1720

Internet

https://www.mdpi.com/1422-0067/22/4/1720

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