A novel substitution matrix fitted to the compositional bias in Mollicutes improves the prediction of homologous relationships
<p>Abstract</p> <p>Background</p> <p>Substitution matrices are key parameters for the alignment of two protein sequences, and consequently for most comparative genomics studies. The composition of biological sequences can vary importantly between species and groups of s...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2011-11-01
|
Series: | BMC Bioinformatics |
Online Access: | http://www.biomedcentral.com/1471-2105/12/457 |