Monitoring voltage fluctuations of intracellular membranes

Abstract In eukaryotic cells, the endoplasmic reticulum (ER) is the largest continuous membrane-enclosed network which surrounds a single lumen. Using a new genetically encoded voltage indicator (GEVI), we applied the patch clamp technique to cultured HEK293 cells and neurons and found that there is...

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Bibliographic Details
Main Authors: Masoud Sepehri Rad, Lawrence B. Cohen, Oliver Braubach, Bradley J. Baker
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25083-7