Pathogenicity and Immunogenicity of Recombinant Rabies Viruses Expressing the Lagos Bat Virus Matrix and Glycoprotein: Perspectives for a Pan-Lyssavirus Vaccine

Pathogenicity and Immunogenicity of Recombinant Rabies Viruses Expressing the Lagos Bat Virus Matrix and Glycoprotein: Perspectives for a Pan-Lyssavirus Vaccine

Lagos bat virus (LBV) is a phylogroup II lyssavirus exclusively found in Africa. Previous studies indicated that this virus is lethal to mice after intracranial and intramuscular inoculation. The antigenic composition of LBV differs substantially from that of rabies virus (RABV) and current rabies v...

Full description

Bibliographic Details
Main Authors: Joe Kgaladi, Milosz Faber, Bernhard Dietzschold, Louis H. Nel, Wanda Markotter
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Tropical Medicine and Infectious Disease
Subjects:
rabies
vaccines
Africa
lyssavirus
pathogenesis
recombinant viruses
Online Access:https://www.mdpi.com/2414-6366/2/3/37

Internet

https://www.mdpi.com/2414-6366/2/3/37

Similar Items