Limited Generalizability of Registration Trials in Hepatitis C: A Nationwide Cohort Study.

Limited Generalizability of Registration Trials in Hepatitis C: A Nationwide Cohort Study.

BACKGROUND:Approval of drugs in chronic hepatitis C is supported by registration trials. These trials might have limited generalizability through use of strict eligibility criteria. We compared effectiveness and safety of real world hepatitis C patients eligible and ineligible for registration trial...

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Bibliographic Details
Main Authors: Floor A C Berden, Robert J de Knegt, Hans Blokzijl, Sjoerd D Kuiken, Karel J L van Erpecum, Sophie B Willemse, Jan den Hollander, Marit G A van Vonderen, Pieter Friederich, Bart van Hoek, Carin M J van Nieuwkerk, Joost P H Drenth, Wietske Kievit
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5012685?pdf=render

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http://europepmc.org/articles/PMC5012685?pdf=render

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