The structure-based cancer-related single amino acid variation prediction
Abstract Single amino acid variation (SAV) is an amino acid substitution of the protein sequence that can potentially influence the entire protein structure or function, as well as its binding affinity. Protein destabilization is related to diseases, including several cancers, although using traditi...
Main Authors: | Jia-Jun Liu, Chin-Sheng Yu, Hsiao-Wei Wu, Yu-Jen Chang, Chih-Peng Lin, Chih-Hao Lu |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-06-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-92793-w |
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