Detection and Quantification of Fluorescent Cell Clusters in Cryo-Imaging

We developed and evaluated an algorithm for enumerating fluorescently labeled cells (e.g., stem and cancer cells) in mouse-sized, microscopic-resolution, cryo-image volumes. Fluorescent cell clusters were detected, segmented, and then fit with a model which incorporated a priori information about ce...

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Bibliographic Details
Main Authors: Grant J. Steyer, Feng Dong, Lehar Kanodia, Debashish Roy, Marc Penn, David L. Wilson
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:International Journal of Biomedical Imaging
Online Access:http://dx.doi.org/10.1155/2012/698413