Tetanus: Pathophysiology, Treatment, and the Possibility of Using Botulinum Toxin against Tetanus-Induced Rigidity and Spasms

Tetanus toxin, the product of Clostridium tetani, is the cause of tetanus symptoms. Tetanus toxin is taken up into terminals of lower motor neurons and transported axonally to the spinal cord and/or brainstem. Here the toxin moves trans-synaptically into inhibitory nerve terminals, where vesicular r...

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Bibliographic Details
Main Author: Bjørnar Hassel
Format: Article
Language:English
Published: MDPI AG 2013-01-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/5/1/73