Chromosome Missegregation and Trisomy 21 Mosaicism in Alzheimer's Disease
A connection between Alzheimer's disease (AD) and Down syndrome (trisomy 21) is indicated by the fact that all Down syndrome individuals develop Alzheimer's disease neuropathology by the 4th decade of life. Previous studies have examined the frequency of aneuploidy and other chromosomal de...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
1999-06-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S096999619990236X |