Chromosome Missegregation and Trisomy 21 Mosaicism in Alzheimer's Disease

A connection between Alzheimer's disease (AD) and Down syndrome (trisomy 21) is indicated by the fact that all Down syndrome individuals develop Alzheimer's disease neuropathology by the 4th decade of life. Previous studies have examined the frequency of aneuploidy and other chromosomal de...

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Bibliographic Details
Main Authors: Lisa N. Geller, Huntington Potter
Format: Article
Language:English
Published: Elsevier 1999-06-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S096999619990236X