ADAR3 expression is an independent prognostic factor in lower-grade diffuse gliomas and positively correlated with the editing level of GRIA2Q607R

ADAR3 expression is an independent prognostic factor in lower-grade diffuse gliomas and positively correlated with the editing level of GRIA2Q607R

Abstract Background RNA editing by adenosine deaminases acting on RNA (ADARs) converts adenosines to inosines (A-to-I) in RNA, that alters gene expression and generates protein diversity. Dysregulation of A-to-I editing has been found associated with a number of nervous system diseases. However, the...

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Bibliographic Details
Main Authors: Ying Zhang, Kuanyu Wang, Zheng Zhao, Si Sun, Kenan Zhang, Ruoyu Huang, Fan Zeng, Huimin Hu
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Cancer Cell International
Subjects:
ADAR3
A-to-I editing
Prognosis
GRIA2Q607R
Lower-grade glioma
Online Access:http://link.springer.com/article/10.1186/s12935-018-0695-8

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http://link.springer.com/article/10.1186/s12935-018-0695-8

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