Degradation of the disease-associated prion protein by a serine protease from lichens.

The disease-associated prion protein (PrP(TSE)), the probable etiological agent of the transmissible spongiform encephalopathies (TSEs), is resistant to degradation and can persist in the environment. Lichens, mutualistic symbioses containing fungi, algae, bacteria and occasionally cyanobacteria, ar...

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Bibliographic Details
Main Authors: Christopher J Johnson, James P Bennett, Steven M Biro, Juan Camilo Duque-Velasquez, Cynthia M Rodriguez, Richard A Bessen, Tonie E Rocke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21589935/pdf/?tool=EBI