Longitudinal data analysis for rare variants detection with penalized quadratic inference function

Abstract Longitudinal genetic data provide more information regarding genetic effects over time compared with cross-sectional data. Coupled with next-generation sequencing technologies, it becomes reality to identify important genes containing both rare and common variants in a longitudinal design....

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Bibliographic Details
Main Authors: Hongyan Cao, Zhi Li, Haitao Yang, Yuehua Cui, Yanbo Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2017-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00712-9