Long term maintenance of myeloid leukemic stem cells cultured with unrelated human mesenchymal stromal cells

Long term maintenance of myeloid leukemic stem cells cultured with unrelated human mesenchymal stromal cells

Mesenchymal stromal cells (MSCs) support the growth and differentiation of normal hematopoietic stem cells (HSCs). Here we studied the ability of MSCs to support the growth and survival of leukemic stem cells (LSCs) in vitro. Primary leukemic blasts isolated from the peripheral blood of 8 patients w...

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Bibliographic Details
Main Authors: Sawa Ito, A. John Barrett, Amalia Dutra, Evgenia Pak, Samantha Miner, Keyvan Keyvanfar, Nancy F. Hensel, Katayoun Rezvani, Pawel Muranski, Paul Liu, J. Joseph Melenhorst, Andre Larochelle
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506114001433

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http://www.sciencedirect.com/science/article/pii/S1873506114001433

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