Genome-Guided Discovery of Pretilactam from <i>Actinosynnema pretiosum</i> ATCC 31565

Genome-Guided Discovery of Pretilactam from <i>Actinosynnema pretiosum</i> ATCC 31565

<i>Actinosynnema</i> is a small but well-known genus of actinomycetes for production of ansamitocin, the payload component of antibody-drug conjugates against cancers. However, the secondary metabolite production profile of <i>Actinosynnema pretiosum</i> ATCC 31565, the most...

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Bibliographic Details
Main Authors: Jing Wang, Xiaowen Hu, Guizhi Sun, Linli Li, Bingya Jiang, Shufen Li, Liping Bai, Hongyu Liu, Liyan Yu, Linzhuan Wu
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Molecules
Subjects:
<i>Actinosynnema pretiosum</i> ATCC 31565
polyene macrolactam
pretilactam
antiSMASH
Online Access:https://www.mdpi.com/1420-3049/24/12/2281

Internet

https://www.mdpi.com/1420-3049/24/12/2281

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