TGFβ1 orchestrates renal fibrosis following Escherichia coli pyelonephritis

Abstract Renal scarring after pyelonephritis is linked to long‐term health risks for hypertension and chronic kidney disease. Androgen exposure increases susceptibility to, and severity of, uropathogenic Escherichia coli (UPEC) pyelonephritis and resultant scarring in both male and female mice, whil...

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Bibliographic Details
Main Authors: Teri N. Hreha, Christina A. Collins, Allyssa L. Daugherty, Joy Twentyman, Nitin Paluri, David A. Hunstad
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.14401