Inhibitory effects of class I antiarrhythmic agents on Na+ and Ca2+ currents of human iPS cell-derived cardiomyocytes

Introduction: Human induced pluripotent stem cells (hiPSCs) harboring cardiac myosin heavy chain 6 promoter can differentiate into functional cardiomyocytes called “iCell cardiomyocytes” under blasticidin treatment condition. While iCell cardiomyocytes are expected to be used for predicting cardioto...

Full description

Bibliographic Details
Main Authors: Sayaka Yonemizu, Keiichiro Masuda, Yasutaka Kurata, Tomomi Notsu, Yuhei Higashi, Kenta Fukumura, Peili Li, Haruaki Ninomiya, Junichiro Miake, Motokazu Tsuneto, Yasuaki Shirayoshi, Ichiro Hisatome
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Regenerative Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320418300646