A mechanical model of cell segregation driven by differential adhesion.

From simulations that begin with a random mix of two cell types, we monitor progress towards segregation driven by contact-mediated linkage of model cells, which is equivalent to the cell-cell adhesion of real cells. In comparison with real cell experiments, we show that this mechanical model can ac...

Full description

Bibliographic Details
Main Authors: William R Taylor, Rosalind Morley, Alexey Krasavin, Lauren Gregory, David G Wilkinson, Alexei Poliakov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3430666?pdf=render