Structural studies of the tandem Tudor domains of fragile X mental retardation related proteins FXR1 and FXR2.

Structural studies of the tandem Tudor domains of fragile X mental retardation related proteins FXR1 and FXR2.

Expansion of the CGG trinucleotide repeat in the 5'-untranslated region of the FMR1, fragile X mental retardation 1, gene results in suppression of protein expression for this gene and is the underlying cause of Fragile X syndrome. In unaffected individuals, the FMRP protein, together with two...

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Bibliographic Details
Main Authors: Melanie A Adams-Cioaba, Yahong Guo, ChuanBing Bian, Maria F Amaya, Robert Lam, Gregory A Wasney, Masoud Vedadi, Chao Xu, Jinrong Min
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2970552?pdf=render

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http://europepmc.org/articles/PMC2970552?pdf=render

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