Effect of the IL-1 Receptor Antagonist Kineret® on Disease Phenotype in mdx Mice.

Duchenne muscular dystrophy (DMD) is an X-linked muscle disease caused by mutations in the dystrophin gene. The pathology of DMD manifests in patients with progressive muscle weakness, loss of ambulation and ultimately death. One of the characteristics of DMD is muscle inflammation, and dystrophin-d...

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Bibliographic Details
Main Authors: Margaret E Benny Klimek, Arpana Sali, Sree Rayavarapu, Jack H Van der Meulen, Kanneboyina Nagaraju
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4877010?pdf=render