Distinct physical condition and social behavior phenotypes of CD157 and CD38 knockout mice during aging.

The ability of CD38 and CD157 to utilize nicotinamide adenine dinucleotide (NAD) has received much attention because the aging-induced elevation of CD38 expression plays a role in the senescence-related decline in NAD levels. Therefore, it is of interest to examine and compare the effects of age-ass...

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Main Authors: Maria Gerasimenko, Olga Lopatina, Anna A Shabalova, Stanislav M Cherepanov, Alla B Salmina, Shigeru Yokoyama, Hisanori Goto, Hiroshi Okamoto, Yasuhiko Yamamoto, Katsuhiko Ishihara, Haruhiro Higashida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0244022