Gene expression profiling of long-lived dwarf mice: longevity-associated genes and relationships with diet, gender and aging

<p>Abstract</p> <p>Background</p> <p>Long-lived strains of dwarf mice carry mutations that suppress growth hormone (GH) and insulin-like growth factor I (IGF-I) signaling. The downstream effects of these endocrine abnormalities, however, are not well understood and it i...

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Bibliographic Details
Main Author: Swindell William R
Format: Article
Language:English
Published: BMC 2007-10-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/8/353