Microglia in the Alzheimer's brain: a help or a hindrance?

Alzheimer’s disease (AD), the leading cause of dementia, is a complex neurodegenerative disorder. The AD brain is characterized by the presence of Amyloid-β (Aβ) plaques, neurofibrillary tangles, and an increased inflammatory response. Microglia, the chief immune cells of the central nervous system,...

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Bibliographic Details
Main Authors: Craig T. Vollert, Jason L. Eriksen
Format: Article
Language:English
Published: AIMS Press 2014-12-01
Series:AIMS Neuroscience
Subjects:
Online Access:http://www.aimspress.com/neuroscience/article/122/fulltext.html