Neopterin May Enhance TNF-a-mediated Mononuclear Cell Death in the Cerebrospinal Fluid of Patients with Bacterial Meningitis

Neopterin May Enhance TNF-a-mediated Mononuclear Cell Death in the Cerebrospinal Fluid of Patients with Bacterial Meningitis

It has been reported that levels of neopterin are elevated in the cerebrospinal fluid (CSF) of patients with bacterial meningitis, and that neopterin enhances cell death induced by H2O2 in mouse monocytes and macrophages. In the present study, we examined the relationship between the disappearance o...

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Bibliographic Details
Main Authors: Kawakami Yasuhiko, Tsukimoto Mitsutoshi, Kuwabara Kentaro, Fujita Takehisa, Fujino Osamu, Kojima Shuji, Fukunaga Yoshitaka
Format: Article
Language:English
Published: De Gruyter 2011-02-01
Series:Pteridines
Subjects:
neopterin
tumor necrosis factor-alpha
bacterial meningitis
polymorphonuclear leukocytes
mononuclear leukocytes
cerebrospinal fluid
cell death
Online Access:https://doi.org/10.1515/pteridines.2011.22.1.91

Internet

https://doi.org/10.1515/pteridines.2011.22.1.91

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