Ixabepilone development across the breast cancer continuum: a paradigm shift

Nuhad K IbrahimDepartment of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USAAbstract: The epothilone analog ixabepilone exhibits reduced susceptibility to several important tumor survival mechanisms that limit the efficacy of taxanes and anthracyclines. A...

Full description

Bibliographic Details
Main Author: Nuhad K Ibrahim
Format: Article
Language:English
Published: Dove Medical Press 2010-06-01
Series:Cancer Management and Research
Online Access:http://www.dovepress.com/ixabepilone-development-across-the-breast-cancer-continuum-a-paradigm--a4719