Development of a screening strategy for new modulators of T cell receptor signaling and T cell activation
Abstract Activation of the T cell receptor (TCR) leads to the generation of a network of signaling events critical to the developmental decision making and activation of T cells. Various experimental approaches continue to identify new signaling molecules, adaptor proteins, and other regulators of T...
Main Authors: | Elijah W. Chen, Joanna Brzostek, Nicholas R. J. Gascoigne, Vasily Rybakin |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-018-28106-5 |
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