JMJD-5/KDM8 regulates H3K36me2 and is required for late steps of homologous recombination and genome integrity.
The eukaryotic genome is organized in a three-dimensional structure called chromatin, constituted by DNA and associated proteins, the majority of which are histones. Post-translational modifications of histone proteins greatly influence chromatin structure and regulate many DNA-based biological proc...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2017-02-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC5336306?pdf=render |