IFN-γ-induced increase in the mobility of MHC class II compartments in astrocytes depends on intermediate filaments

IFN-γ-induced increase in the mobility of MHC class II compartments in astrocytes depends on intermediate filaments

<p>Abstract</p> <p>Background</p> <p>In immune-mediated diseases of the central nervous system, astrocytes exposed to interferon-γ (IFN-γ) can express major histocompatibility complex (MHC) class II molecules and antigens on their surface. MHC class II molecules are tho...

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Bibliographic Details
Main Authors: Vardjan Nina, Gabrijel Mateja, Potokar Maja, Švajger Urban, Kreft Marko, Jeras Matjaž, de Pablo Yolanda, Faiz Maryam, Pekny Milos, Zorec Robert
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Journal of Neuroinflammation
Subjects:
Astrocytes
Vesicle mobility
Late endosomes/lysosomes
Major histocompatibility class II compartments
Interferon-γ
Dextran labeling
Immune response
Online Access:http://www.jneuroinflammation.com/content/9/1/144

Internet

http://www.jneuroinflammation.com/content/9/1/144

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