Prediction of gene expression with cis-SNPs using mixed models and regularization methods

Prediction of gene expression with cis-SNPs using mixed models and regularization methods

Abstract Background It has been shown that gene expression in human tissues is heritable, thus predicting gene expression using only SNPs becomes possible. The prediction of gene expression can offer important implications on the genetic architecture of individual functional associated SNPs and furt...

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Bibliographic Details
Main Authors: Ping Zeng, Xiang Zhou, Shuiping Huang
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Genomics
Subjects:
Gene expression
Cis-SNPs
Prediction model
Linear mixed model
Lasso
Elastic net
Online Access:http://link.springer.com/article/10.1186/s12864-017-3759-6

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http://link.springer.com/article/10.1186/s12864-017-3759-6

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