Highly efficient protein misfolding cyclic amplification.

Highly efficient protein misfolding cyclic amplification.

Protein misfolding cyclic amplification (PMCA) provides faithful replication of mammalian prions in vitro and has numerous applications in prion research. However, the low efficiency of conversion of PrP(C) into PrP(Sc) in PMCA limits the applicability of PMCA for many uses including structural stud...

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Bibliographic Details
Main Authors: Nuria Gonzalez-Montalban, Natallia Makarava, Valeriy G Ostapchenko, Regina Savtchenk, Irina Alexeeva, Robert G Rohwer, Ilia V Baskakov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3037363?pdf=render

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http://europepmc.org/articles/PMC3037363?pdf=render

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