To bind or not to bind – how to down-regulate target genes by liganded thyroid hormone receptor?

<p>Abstract</p> <p>The terrain is well explored regarding genes whose gene expression is up-regulated upon binding of thyroid hormone (TH) to its nuclear receptor. This regulation mechanism has been intensively studied and is well understood. In contrast, a lot of white spots remai...

Full description

Bibliographic Details
Main Author: Weitzel Joachim M
Format: Article
Language:English
Published: BMC 2008-10-01
Series:Thyroid Research
Online Access:http://www.thyroidresearchjournal.com/content/1/1/4