Analysis to Estimate Genetic Variations in the Idarubicin-Resistant Derivative MOLT-3

Analysis to Estimate Genetic Variations in the Idarubicin-Resistant Derivative MOLT-3

Gene alterations are a well-established mechanism leading to drug resistance in acute leukemia cells. A full understanding of the mechanisms of drug resistance in these cells will facilitate more effective chemotherapy. In this study, we investigated the mechanism(s) of drug resistance in the human...

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Bibliographic Details
Main Authors: Tomoyoshi Komiyama, Atsushi Ogura, Takatsugu Hirokawa, Miao Zhijing, Hiroshi Kamiguchi, Satomi Asai, Hayato Miyachi, Hiroyuki Kobayashi
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:International Journal of Molecular Sciences
Subjects:
leukemia
MOLT-3
GALNT2 gene
gene polymorphism
mitochondrial DNA
CGH array
genetic variations
idarubicin (IDR)
Online Access:http://www.mdpi.com/1422-0067/18/1/12

Internet

http://www.mdpi.com/1422-0067/18/1/12

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