Integrated Nanosensors to Determine Levels and Functional Activity of Human Telomerase

Telomerase is a key oncogenic enzyme, and a number of novel telomerase inhibitors are currently under development. Because inhibition can be achieved either at the protein or at the enzymatic activity level, independent measurements of these parameters are important in the development of effective...

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Bibliographic Details
Main Authors: J. Manuel Perez, Jan Grimm, Lee Josephson, Ralph Weissleder
Format: Article
Language:English
Published: Elsevier 2008-10-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558608800978