Multivalent Fusion DNA Vaccine against Brucella abortus
As an alternative brucellosis prevention method, we evaluated the immunogenicity induced by new multivalent DNA vaccines in BALB/c mice. We constructed the vaccines by fusion of BAB1_0273 and/or BAB1_0278 open reading frames (ORFs) from genomic island 3 (GI-3) and the Brucella abortus 2308 sodC gene...
Main Authors: | Leonardo Gómez, Javiera Llanos, Emilia Escalona, Darwin Sáez, Francisco Álvarez, Raúl Molina, Manuel Flores, Angel Oñate |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2017-01-01
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2017/6535479 |
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