Multivalent Fusion DNA Vaccine against Brucella abortus

As an alternative brucellosis prevention method, we evaluated the immunogenicity induced by new multivalent DNA vaccines in BALB/c mice. We constructed the vaccines by fusion of BAB1_0273 and/or BAB1_0278 open reading frames (ORFs) from genomic island 3 (GI-3) and the Brucella abortus 2308 sodC gene...

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Bibliographic Details
Main Authors: Leonardo Gómez, Javiera Llanos, Emilia Escalona, Darwin Sáez, Francisco Álvarez, Raúl Molina, Manuel Flores, Angel Oñate
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2017/6535479