Glucokinase gene mutations: structural and genotype-phenotype analyses in MODY children from South Italy.

Glucokinase gene mutations: structural and genotype-phenotype analyses in MODY children from South Italy.

BACKGROUND: Maturity onset diabetes of the young type 2 (or GCK MODY) is a genetic form of diabetes mellitus provoked by mutations in the glucokinase gene (GCK). METHODOLOGY/PRINCIPAL FINDINGS: We screened the GCK gene by direct sequencing in 30 patients from South Italy with suspected MODY. The mut...

Full description

Bibliographic Details
Main Authors: Nadia Tinto, Adriana Zagari, Marina Capuano, Alfonso De Simone, Valentina Capobianco, Gerardo Daniele, Michela Giugliano, Raffaella Spadaro, Adriana Franzese, Lucia Sacchetti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2270336?pdf=render

Internet

http://europepmc.org/articles/PMC2270336?pdf=render

Similar Items