Antimicrobial and Hypoglycemic Activities of Novel N-Mannich Bases Derived from 5-(1-Adamantyl)-4-substituted-1,2,4-triazoline-3-thiones

Antimicrobial and Hypoglycemic Activities of Novel N-Mannich Bases Derived from 5-(1-Adamantyl)-4-substituted-1,2,4-triazoline-3-thiones

The reaction of 5-(1-adamantyl)-4-ethyl or allyl-1,2,4-triazoline-3-thione with formaldehyde solution and various 1-substituted piperazines yielded the corresponding N-Mannich bases. The newly synthesized N-Mannich bases were tested for in vitro inhibitory activities against a panel of Gram-positiv...

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Bibliographic Details
Main Authors: Ebtehal S. Al-Abdullah, Hanaa M. Al-Tuwaijri, Hanan M. Hassan, Mogedda E. Haiba, Elsayed E. Habib, Ali A. El-Emam
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:International Journal of Molecular Sciences
Subjects:
adamantane derivatives
1,2,4-triazoles
N-Mannich bases
antimicrobial activity
hypoglycemic activity
Online Access:http://www.mdpi.com/1422-0067/15/12/22995

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http://www.mdpi.com/1422-0067/15/12/22995

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