ss-TEA: Entropy based identification of receptor specific ligand binding residues from a multiple sequence alignment of class A GPCRs

<p>Abstract</p> <p>Background</p> <p>G-protein coupled receptors (GPCRs) are involved in many different physiological processes and their function can be modulated by small molecules which bind in the transmembrane (TM) domain. Because of their structural and sequence c...

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Bibliographic Details
Main Authors: Alkema Wynand, van den Beld Sven, Verhoeven Stefan, Fleuren Wilco WM, Sanders Marijn PA, de Vlieg Jacob, Klomp Jan PG
Format: Article
Language:English
Published: BMC 2011-08-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/332