Expression of the B-cell receptor component CD79a on immature myeloid cells contributes to their tumor promoting effects.

The role of myeloid derived suppressor cells (MDSCs) in promoting tumorigenesis is well-established, and significant effort is being made to further characterize surface markers on MDSCs both for better diagnosis and as potential targets for therapy. Here we show that the B cell receptor adaptor mol...

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Bibliographic Details
Main Authors: Dror Luger, Yu-An Yang, Asaf Raviv, Douglas Weinberg, Subhadra Banerjee, Min-Jung Lee, Jane Trepel, Li Yang, Lalage M Wakefield
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3797715?pdf=render