Fully automated leg tracking of Drosophila neurodegeneration models reveals distinct conserved movement signatures.

Fully automated leg tracking of Drosophila neurodegeneration models reveals distinct conserved movement signatures.

Some neurodegenerative diseases, like Parkinsons Disease (PD) and Spinocerebellar ataxia 3 (SCA3), are associated with distinct, altered gait and tremor movements that are reflective of the underlying disease etiology. Drosophila melanogaster models of neurodegeneration have illuminated our understa...

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Bibliographic Details
Main Authors: Shuang Wu, Kah Junn Tan, Lakshmi Narasimhan Govindarajan, James Charles Stewart, Lin Gu, Joses Wei Hao Ho, Malvika Katarya, Boon Hui Wong, Eng-King Tan, Daiqin Li, Adam Claridge-Chang, Camilo Libedinsky, Li Cheng, Sherry Shiying Aw
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-06-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000346

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https://doi.org/10.1371/journal.pbio.3000346

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