Mutagenesis of the fusion peptide-like domain of hepatitis C virus E1 glycoprotein: involvement in cell fusion and virus entry

<p>Abstract</p> <p>Background</p> <p>Envelope (E) glycoprotein E2 of the hepatitis C virus (HCV) mediates binding of the virus to target cell receptors. Nevertheless, the precise role of E1 in viral entry remains elusive.</p> <p>Methods</p> <p>To...

Full description

Bibliographic Details
Main Authors: Chuang Chin-Kai, Ai Li-Shuang, Huang Chia-Hsuan, Li Hsiao-Fen, Chen Steve SL
Format: Article
Language:English
Published: BMC 2009-09-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/16/1/89